The Effect of Alexander the Great on Europe

Alexander the Great's relation to triumph is obvious, he created an army which took over most of the known world. But what is not known widely is how tragic his life was. I cannot do full justice to his life but I will do my best to describe it.
When Alexander was a child his parents were constantly fighting and his father was usually away on campaigns, so he rarely saw him when he was young.   He therefore was usually under his mother's influence.
When he was a young man his father was killed and he had to take over an entire country by himself which was in very bad shape.   As he grew he had to deal with disputes, revolts and cruel neighboring rivals.
When he was a grown man he killed many people, including some of his friends while in a drunken rage who had saved his life.   At one point in his life he killed a life long friend while drunk and then realizing what he had done would have killed himself if his bodyguards had not restrained him.   He then went into seclusion for three days.
This is most likely just a small number of things that shaped Alexander the Great's life and it is likely some of the memories tormented him through most of his life.   Most of Alexander's life was one big problem after another.   I personally think it would have been hard to live with the blood of so many friends deaths on my hands, but maybe he could.
Apart from the immense increase of international trade and the fraternization of many nations, what were the results, temporary and enduring, of the career of this great man?   Of supreme and lasting importance to the world was the extension of Greek culture; secondly, a vast territory was opened up which had been useless as a desert until the conquered nomad tribes had been trained to follow civilized ways of life.   This included the incentive to build cities, create harbors, ships and other aids for travel on land and sea; thirdly, financial and economic reforms; and lastly, the partial realization of Alexander's dream of...